The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2006
Filed:
Jan. 02, 2002
Ronnie C. Hanecak, San Clemente, CA (US);
Kevin P. Anderson, Carlsbad, CA (US);
C. Frank Bennett, Carlsbad, CA (US);
Ming-yi Chiang, San Diego, CA (US);
Vickie L. Brown-driver, Solana Beach, CA (US);
David J. Ecker, Encinitas, CA (US);
Timothy A. Vickers, Oceanside, CA (US);
Jacqueline R. Wyatt, Encinitas, CA (US);
Ronnie C. Hanecak, San Clemente, CA (US);
Kevin P. Anderson, Carlsbad, CA (US);
C. Frank Bennett, Carlsbad, CA (US);
Ming-Yi Chiang, San Diego, CA (US);
Vickie L. Brown-Driver, Solana Beach, CA (US);
David J. Ecker, Encinitas, CA (US);
Timothy A. Vickers, Oceanside, CA (US);
Jacqueline R. Wyatt, Encinitas, CA (US);
ISIS Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
Modified oligonucleotides having a GGG motif sequence and a sufficient number of flanking nucleotides to modulate the telomere length of a chromosome are provided. Methods of modulating telomere length of a mammalian chromosome in vitro and in vivo are also provided, as are methods for inhibiting the division of a malignant mammalian cell and for modulating the effects of cellular aging.