The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2006
Filed:
Aug. 17, 2000
Walter Birchmeier, Schwanebeck, DE;
Jens-peter Von Kries, Zepernick, DE;
Walter Birchmeier, Schwanebeck, DE;
Jens-Peter Von Kries, Zepernick, DE;
Abstract
The present invention relates to peptides that affect the interaction of the protein β-catenin with a transcription factor or a tumor suppressor protein. Such peptides are derived either from the amino acids of β-catenin that are known to interact with such proteins, or from the amino acids of the transcription factor or tumor suppressor protein that are known to interact with β-catenin. The effect of the interaction is preferably inhibition of binding of β-catenin and the transcription factor or tumor suppressor protein. Peptide mutants and peptidomimetic compounds are also contemplated in the invention. The peptides, mutands and peptidomimetic compounds of the invention are useful for treating cancer in mammals, and particularly in humans.