The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2006
Filed:
Mar. 15, 2002
Robert M. Corn, Madison, WI (US);
Emily A. Smith, Madison, WI (US);
Bernard Weisblum, Madison, WI (US);
Matthew G. Erickson, Madison, WI (US);
Andrew T. Ulijasz, Madison, WI (US);
Matthew J. Wanat, Madison, WI (US);
Robert M. Corn, Madison, WI (US);
Emily A. Smith, Madison, WI (US);
Bernard Weisblum, Madison, WI (US);
Matthew G. Erickson, Madison, WI (US);
Andrew T. Ulijasz, Madison, WI (US);
Matthew J. Wanat, Madison, WI (US);
Wisconsin Alumni Research Foundation, Madison, WI (US);
Abstract
Disclosed are methods for making surface plasmon resonance-capable arrays wherein molecules, such as proteins or nucleic acids, or cells, are adhered to a metal substrate. The metal substrates are modified by depositing an ω-modified alkanethiol monolayer to the substrate and then contacting the ω-modified monolayer with a heterobifunctional linking compound. Biomolecules or cells can then be attached to the heterobifunctional linking compound. Also disclosed are arrays wherein glutathione-containing molecules are immobilized on the substrate and GST-containing molecules are then specifically immobilized onto the substrate, taking advantage of the affinity between glutathione and GST.