The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2006
Filed:
Dec. 20, 2002
Applicants:
David R. Allen, LaGrange Park, IL (US);
Vadim V. Mozhaev, Hoffman Estates, IL (US);
Rao H. Valivety, Schaumburg, IL (US);
Inventors:
David R. Allen, LaGrange Park, IL (US);
Vadim V. Mozhaev, Hoffman Estates, IL (US);
Rao H. Valivety, Schaumburg, IL (US);
Assignee:
Pfizer Inc., New York, NY (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P 13/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods for preparing enantiomerically enriched aminopentanenitriles are provided. The methods involve selective acylation of an enantiomeric mixture of 3-aminopentanenitrile or selective hydrolysis of an enantiomeric mixture of 3-aminopentanenitrile amide in the presence of an enzyme selected from the group comprising lipase, esterase, and acylase. The methods yield R-aminopentanenitrile, which can be used to produce pharmaceutical products.