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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7067269 B1

PDFFull Text
Date of Patent:
Jun. 27, 2006

Filed:

Nov. 26, 2001

Assaying apparatus, kit, and method for lipids and associated enzymes

Applicants:

Beth E. Drees, Park City, UT (US);

Glenn D. Prestwich, Salt Lake City, UT (US);

Paul O. Neilsen, Draper, UT (US);

Leena Chakravarty, Sandy, UT (US);

Michael J. Mostert, Salt Lake City, UT (US);

Inventors:

Beth E. Drees, Park City, UT (US);

Glenn D. Prestwich, Salt Lake City, UT (US);

Paul O. Neilsen, Draper, UT (US);

Leena Chakravarty, Sandy, UT (US);

Michael J. Mostert, Salt Lake City, UT (US);

Assignee:

Echelon Biosciences, Inc., Salt Lake City, UT (US);

Attorney:

The McCallum Law Firm

Primary Examiner:

Long V Le

Assistant Examiner:

Gary W Counts

Int. Cl.
CPC ...
G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract

A lipid assay method, kit, and apparatus involving exposure of a protein, having a lipid recognition motif that interacts with a target lipid and a competing lipid, to a solution containing the competing lipid, and determining whether the target lipid is present in the solution. The target lipid has a stronger affinity to the lipid recognition motif than does the competing lipid. The lipid recognition motif is preferably a pleckstrin homology (PH) domain, with the target lipid being a phosphoinositide. The assay determines activity of a lipid kinase, the target lipid being a phosphorylation product of a reaction between the lipid kinase and a substrate lipid. The assay can be a cancer screening method for detection of cancer cells, where detection of certain levels of a PI(3,4,5)Ptarget lipid is an indicator of a cancer cell.

Find Patent Forward Citations

Drees, Beth. (2006). Assaying apparatus, kit, and method for lipids and associated enzymes (U.S. Patent No. 7067269). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7067269

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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