The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 27, 2006
Filed:
Aug. 08, 2002
Richard S. Blumberg, Chestnut Hill, MA (US);
Neil E. Simister, Wellesley, MA (US);
Wayne I. Lencer, Jamaica Plain, MA (US);
Richard S. Blumberg, Chestnut Hill, MA (US);
Neil E. Simister, Wellesley, MA (US);
Wayne I. Lencer, Jamaica Plain, MA (US);
The Brigham and Woman's Hospital, Inc., Boston, MA (US);
Brandeis University, Waltham, MA (US);
Abstract
The present invention relates in general to methods and products for initiating an immune response against an antigen, and in particular relates to transepithelial delivery of antigens to provoke tolerance and immunity. The present invention further relates to methods and products for the transepithelial delivery of therapeutics. In particular, the invention relates to methods and compositions for the delivery of therapeutics conjugated to a FcRn binding partner to intestinal epithelium, mucosal epithelium and epithelium of the lung. The present invention further relates to the synthesis, preparation and use of the FcRn binding partner conjugates as, or in, pharmaceutical compositions for oral systemic delivery of drugs and vaccines.