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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 7064243 B1

PDFFull Text
Expired
Date of Patent:
Jun. 20, 2006

Filed:

Jan. 18, 2002

Screens and assays for agents useful in controlling parasitic nematodes

Applicants:

Leo Liu, Weston, MA (US);

Lucinda Burnam, Somerville, MA (US);

Ann Sluder, Burlington, MA (US);

Elizabeth Link, Brentwood, TN (US);

Beth Westlund, Brookline, MA (US);

Inventors:

Leo Liu, Weston, MA (US);

Lucinda Burnam, Somerville, MA (US);

Ann Sluder, Burlington, MA (US);

Elizabeth Link, Brentwood, TN (US);

Beth Westlund, Brookline, MA (US);

Assignee:

Cambria Biosciences LLC, Bedford, MA (US);

Attorney:

Choate, Hall & Stewart, LLP

Primary Examiner:

Scott D Priebe

Int. Cl.
CPC ...
A01K 67/33 (2006.01); C12N 15/00 (2006.01); G01N 33/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides a method of identifying anti-nematode compounds and further provides transgenic nematodes that may be used to practice the method. In particular, the invention provides a screen for compounds that inhibit a nematode secretion pathway e.g, compounds that inhibit the secretion of proteins by nematodes. The transgenic nematodes express reporters for nematode secreted proteins. In preferred embodiments of the invention the screen is performed using, i.e., certain embodiments of the invention utilizeandsecretory pathways as a model system for parasitic nematodes and parasitic nematode secretion pathways. The invention also provides pharmaceutical compositions that may be used in the treatment and prevention of nematode infection in humans and animals and anti-nematode agents that may be used to protect plants from plant-parasitic nematodes. In addition, the invention provides a genetic screen for identifying additional targets for anti-nematode compounds.

Find Patent Forward Citations

Liu, Leo. (2006). Screens and assays for agents useful in controlling parasitic nematodes (U.S. Patent No. 7064243). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/7064243

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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