The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2006
Filed:
Jan. 15, 2004
Martin Edward Cooper, Loughborough, GB;
Simon David Guile, Loughborough, GB;
Anthony Howard Ingall, Loughborough, GB;
Rukhsana Tasneem Rasul, Loughborough, GB;
Martin Edward Cooper, Loughborough, GB;
Simon David Guile, Loughborough, GB;
Anthony Howard Ingall, Loughborough, GB;
Rukhsana Tasneem Rasul, Loughborough, GB;
AstraZeneca AB, , SE;
Abstract
The invention relates to thienopyridazinones of formula (I): wherein: Ris Calkyl, Calkenyl or Ccycloalkyl which is optionally substituted by Calkyl, each of the above being optionally substituted by one or more halogen atoms; Ris Calkyl; Ris a group CO—G or SO—G where G is a 5- or 6-membered ring containing a nitrogen atom and a second heteroatom selected from oxygen and sulphur adjacent to the nitrogen, and optionally substituted by up to 3 groups selected from hydroxyl and Calkyl; Q is CRRwhere Rand Rare as defined in the specification; and Ris a 5- to 10-membered mono- or bi-cyclic aromatic ring system, containing 0 to 4 heteroatoms independently selected from nitrogen, oxygen and sulphur, the ring system being optionally substituted as described in the specification, and pharmaceutically acceptable salts and solvates thereof. Processes for their preparation, pharmaceutical compositions containing them and their use in therapy, in particular in the modulation of autoimmune disease are also described.