The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 2006

Filed:

Apr. 10, 2002
Applicants:

Amedeo Arturo Failli, Princeton Junction, NJ (US);

Jay Scott Shumsky, Hightstown, NJ (US);

Thomas Joseph Caggiano, Morrisville, PA (US);

Joseph Peter Sabatucci, Collegeville, PA (US);

Kevin Anthony Memoli, Cranbury, NJ (US);

Eugene John Trybulski, Princeton Junction, NJ (US);

Inventors:

Amedeo Arturo Failli, Princeton Junction, NJ (US);

Jay Scott Shumsky, Hightstown, NJ (US);

Thomas Joseph Caggiano, Morrisville, PA (US);

Joseph Peter Sabatucci, Collegeville, PA (US);

Kevin Anthony Memoli, Cranbury, NJ (US);

Eugene John Trybulski, Princeton Junction, NJ (US);

Assignee:

Wyeth, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 15/00 (2006.01); A61K 31/55 (2006.01); C07D 487/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention provides novel substituted tricyclic pyridyl carboxamides which act as oxytocin receptor competitive antagonists, as well as methods of their manufacture, pharmaceutical compositions and methods of their use in treatment, inhibition, suppression or prevention of preterm labor, dysmenorrhea, endometritis, suppression of labor at term prior to caesarean delivery, and to facilitate antinatal transport to a medical facility. These compounds are also useful in enhancing fertility rates, enhancing survival rates and synchronizing estrus in farm animals; and may be useful in the prevention and treatment of disfunctions of the oxytocin system in the central nervous system including obsessive compulsive disorder (OCD) and neuropsychiatric disorders.


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