The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 20, 2006
Filed:
Aug. 27, 2003
Robert Joseph Isfort, Fairfield, OH (US);
Russell James Sheldon, Fairfield, OH (US);
Robert Joseph Isfort, Fairfield, OH (US);
Russell James Sheldon, Fairfield, OH (US);
The Procter & Gamble Company, Cincinnati, OH (US);
Abstract
Screening methods for identifying compounds that bind to or activate corticotropin releasing factorreceptors (CRFR) and regulate or potentially regulate skeletal muscle mass or function in vivo are disclosed. Also disclosed are screening methods for identifying compounds that prolong or augment the activation of CRFRs or of CRFR signal transduction pathways, increase CRFR or increase CRF expression are provided. Pharmaceutical compositions comprising CRFR agonists, antibodies to CRFR and methods for increasing skeletal muscle mass or function or for the treatment of skeletal muscle atrophy using CRFR as the target for intervention and methods for treatment of muscular dystrophies are described.