The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2006

Filed:

Jul. 24, 2000
Applicants:

Lee Arnold, Westborough, MA (US);

Marina Moran Moset, Madrid, ES;

Jose Maria Castellano Berlanga, Madrid, ES;

Isabel Fernandez, Madrid, ES;

David J. Calderwood, Framingham, MA (US);

Paul Rafferty, Nottingham, GB;

Inventors:

Lee Arnold, Westborough, MA (US);

Marina Moran Moset, Madrid, ES;

Jose Maria Castellano Berlanga, Madrid, ES;

Isabel Fernandez, Madrid, ES;

David J. Calderwood, Framingham, MA (US);

Paul Rafferty, Nottingham, GB;

Assignee:

Abbott GmbH & Co. KG, Wiesbaden, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/00 (2006.01); C07D 401/00 (2006.01); C07D 403/00 (2006.01); C07D 411/00 (2006.01); C07D 231/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Chemical compounds having structural formula I and physiologically acceptable salts thereof, are inhibitors of serine/threonine and tyrosine kinase activity. Several of the tyrosine kinases, whose activity is inhibited by these chemical compounds, are involved in angiogenic processes. Thus, these chemical compounds can ameliorate disease states where angiogenesis or endothelial cell hyperproliferation is a factor. These compounds can be used to treat cancer and hyperproliferative disorders.


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