The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 13, 2006

Filed:

Jun. 02, 2005
Applicants:

Hiroshi Kitajima, Tokyo, JP;

Hiroshi Sakashita, Tokyo, JP;

Fumihiko Akahoshi, Tokyo, JP;

Yoshiharu Hayashi, Tokyo, JP;

Inventors:

Hiroshi Kitajima, Tokyo, JP;

Hiroshi Sakashita, Tokyo, JP;

Fumihiko Akahoshi, Tokyo, JP;

Yoshiharu Hayashi, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4025 (2006.01); A61K 31/427 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products. The present inventors have found that derivatives having a substituent introduced into the γ-position of proline represented by the formula (I) wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.


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