The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 06, 2006

Filed:

Aug. 10, 1999
Applicants:

Josephine Egan, Baltimore, MD (US);

Riccardo Perfetti, Washington, DC (US);

Antonino Passaniti, White Hall, MD (US);

Nigel Greig, Silver Spring, MD (US);

Harold Holloway, Middle River, MD (US);

Joel Habener, Newton Centre, MA (US);

Doris Stoffers, Moorestown, NJ (US);

Inventors:

Josephine Egan, Baltimore, MD (US);

Riccardo Perfetti, Washington, DC (US);

Antonino Passaniti, White Hall, MD (US);

Nigel Greig, Silver Spring, MD (US);

Harold Holloway, Middle River, MD (US);

Joel Habener, Newton Centre, MA (US);

Doris Stoffers, Moorestown, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to a population of insulin producing cells made by a process comprising contacting non-insulin producing cells with a growth factor selected from the group consisting of GLP-1 or Exendin-4, growth factors having amino acid sequences substantially homologous to GLP-1 or Exendin-4, and fragmets thereof. The present invention also relates to methods of differentiating non-insulin producing cells into insulin producing cells and of enriching a population of cells for insulin-producing cells. The present invention also relates to methods of treating diabetes.


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