The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 2006
Filed:
Mar. 08, 2002
James Lorens, Portola Valley, CA (US);
Todd M. Kinsella, Fayetteville, NC (US);
Esteban Masuda, Menlo Park, CA (US);
Yasumichi Hitoshi, Mountain View, CA (US);
X. Charlene Liao, Palo Alto, CA (US);
Denise Pearsall, Belmont, CA (US);
Annabelle Freiro, South San Francisco, CA (US);
Peter Chu, San Francisco, CA (US);
James Lorens, Portola Valley, CA (US);
Todd M. Kinsella, Fayetteville, NC (US);
Esteban Masuda, Menlo Park, CA (US);
Yasumichi Hitoshi, Mountain View, CA (US);
X. Charlene Liao, Palo Alto, CA (US);
Denise Pearsall, Belmont, CA (US);
Annabelle Freiro, South San Francisco, CA (US);
Peter Chu, San Francisco, CA (US);
Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);
Abstract
The invention relates to methods and compositions useful for screening for altered cellular phenotypes using an inducible expression system to enrich for and detect the altered phenotypes and, more particularly, relates to screening libraries of candidate bioactive agents, for example, nucleic acids and peptides, in cells using an regulatable expression system to enrich for a subpopulation of cells having an altered phenotype due to the presence of a candidate bioactive agent.