The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
Jul. 02, 2003
Applicants:
Ravindra K. Pandey, Williamsville, NY (US);
Thomas J. Dougherty, Grand Island, NY (US);
Alexander J. Pallenberg, Duvall, WA (US);
Inventors:
Ravindra K. Pandey, Williamsville, NY (US);
Thomas J. Dougherty, Grand Island, NY (US);
Alexander J. Pallenberg, Duvall, WA (US);
Assignee:
Health Research, Inc., Buffalo, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/055 (2006.01); A61B 10/00 (2006.01); C07B 47/00 (2006.01); C07F 5/10 (2006.01); A61K 31/555 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the preparation of pyropheophorbide a and its derivatives, including 3-devinyl-3-(1'-hexyloxy)ethyl-pyropheophorbide-a, otherwise known as HPPH, is provided. The process involves treating chlorin e, in the form of its trimethyl ester, with a base, followed by heating to give pyropheophorbide a, which is converted to HPPH by treatment with acid, followed by hexyl alcohol under basic conditions.