The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
Jan. 28, 2003
Jun Yuan, Guilford, CT (US);
Pamela Albaugh, Carmel, IN (US);
Kenneth Shaw, Weston, CT (US);
Alan Hutchison, Madison, CT (US);
Jun Yuan, Guilford, CT (US);
Pamela Albaugh, Carmel, IN (US);
Kenneth Shaw, Weston, CT (US);
Alan Hutchison, Madison, CT (US);
Neurogen Corporation, Branford, CT (US);
Abstract
Disclosed are compounds of the formula: and the pharmaceutically acceptable salts thereof, wherein W, Q, X, X, Y and Z are as defined herein. These compounds bind with high selectivity and/or high affinity to the benzodiazepine site of GABAreceptors and are therefore useful in the treatment of central nervous system (CNS) diseases and as probes for the localization of GABAreceptors in tissue samples. Also disclosed are intermediates useful in the preparation of these compounds.