The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
Jul. 04, 2000
Zoltan Greff, Budapest, HU;
Geza Szabo, Budapest, HU;
Jozsef Barkoczy, Budapest, HU;
Zoltan Ratkai, Budapest, HU;
Gabor Blasko, Budapest, HU;
Gyula Simig, Budapest, HU;
Gabor Gigler, Budapest, HU;
Bernadett Martonné Marko, Budapest, HU;
György Levay, Budakeszi, HU;
Karoly Tihanyi, Budapest, HU;
Andras Egyed, Budapest, HU;
Annamaria Simo, Budapest, HU;
Zoltan Greff, Budapest, HU;
Geza Szabo, Budapest, HU;
Jozsef Barkoczy, Budapest, HU;
Zoltan Ratkai, Budapest, HU;
Gabor Blasko, Budapest, HU;
Gyula Simig, Budapest, HU;
Gabor Gigler, Budapest, HU;
Bernadett Martonné Marko, Budapest, HU;
György Levay, Budakeszi, HU;
Karoly Tihanyi, Budapest, HU;
Andras Egyed, Budapest, HU;
Annamaria Simo, Budapest, HU;
EGIS Gyogyszergyar Rt., Budapest, HU;
Abstract
The invention relates to new 2,3-benzodiazepine derivatives of general Formula (I), (wherein Rstands for methyl, formyl, carboxy, cyano, —CH═NOH, —CH═NNHCONHor —NRR, wherein Rand Rindependently from each other represent hydrogen or lower alkyl or together with the nitrogen atom, they are attached to, form a 5- or 6-membered, saturated or unsaturated heterocyclic ring optionally containing one or more further nitrogen, sulfur and/or oxygen atom(s); Ris nitro or amino; Rstands for hydrogen, lower alkanoyl or CO—NRR, wherein Rand Rindependently from each other stand for hydrogen, lower alkoxy, lower alkyl or lower cycloalkyl or together with the nitrogen atom, they are attached to, form a 5- or 6-membered, saturated or unsaturated heterocyclic ring optionally containing one or more further nitrogen, sulfur and/or oxygen atom(s); Ris hydrogen or lower alkyl; the dotted lines have the following meaning: if Rand Rare not present, the bond between positions Cand Cis a single bond and the bond between positions Cand Nis a double bond; if Rand Rare present, the bonds between positions Cand Cand between position Cand Nare single bonds; and if Ris present and Ris missing, the bond between positions Cand Cis a double bond and the bond between positions Cand Nis a single bond) and salts thereof. The invention compounds have neuroprotective effect.