The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
Dec. 21, 2001
Applicant:
Kevin Mcgrath, Alpharetta, GA (US);
Inventor:
Kevin McGrath, Alpharetta, GA (US);
Assignee:
Other;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention provides peptide inhibitors that inhibit ubiquitination of hypoxia inducible factor 1 alpha (HIP 1-α) and thereby activate transcription of erythropoietin (EPO), vascular endothelial growth factor (VEGF), and certain glycolytic enzymes. The invention further provides formulations containing the present peptides and methods of using the present peptides for therapeutic purposes. Such therapeutic purposes include stimulating angiogenesis in injured tissues such as chronic wounds, heart tissues injured by ischemia or heart attack, and neural tissues injured by stroke.