The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
Jan. 19, 2001
Se-chang Kwon, Seoul, KR;
Sung-youb Jung, Seoul, KR;
Ki-doo Choi, Seoul, KR;
Cha-soon Kim, Yongin-shi, KR;
Sung-min Bae, Seoul, KR;
Gwan-sun Lee, Seoul, KR;
Se-Chang Kwon, Seoul, KR;
Sung-Youb Jung, Seoul, KR;
Ki-Doo Choi, Seoul, KR;
Cha-Soon Kim, Yongin-shi, KR;
Sung-Min Bae, Seoul, KR;
Gwan-Sun Lee, Seoul, KR;
Hanmi Pharm. Co., Ltd., , KR;
Abstract
Disclosed in this invention are an expression vector for the secretive production of human interferon alpha (hIFNα) comprising a polynucleotide encoding a modifiedthermostable enterotoxin II signal sequence and a polynucleotide encoding hIFNα ligated to the 3'-end thereof; a microorganism transformed with the expression vector; and a process for secretively producing human interferon by culturing the microorganism, the process being capable of secreting a soluble form of active hIFNα, which does not contain an additional methionine residue at its N-terminal, into the periplasm of ancell.