The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 2006
Filed:
Jul. 12, 2000
Ira Pastan, Potomac, MD (US);
Magnus Essand, Uppsala, SE;
Byungkook Lee, Potomac, MD (US);
George Vasmatzis, Byron, MN (US);
Curt Wolfgang, Germantown, MD (US);
Ulrich Brinkmann, Weilheim, DE;
Ira Pastan, Potomac, MD (US);
Magnus Essand, Uppsala, SE;
Byungkook Lee, Potomac, MD (US);
George Vasmatzis, Byron, MN (US);
Curt Wolfgang, Germantown, MD (US);
Ulrich Brinkmann, Weilheim, DE;
Abstract
This invention provides nucleic acids containing sequences from a TCRγ transcript from prostate epithelial cells and many breast cancer cells and a T-cell receptor gamma Alternate Reading frame Protein ('TARP') expressed from the translation of those sequences. Vaccines made from TARP are useful in raising immune responses to cells in which the protein is expressed, including prostate cancer cells and cells of many breast cancers. The invention also provides methods for diagnosing the presence of prostate cancer and TARP-expressing breast cancers, as well as methods of administering TARP and nucleic acids encoding TARP to subjects.