The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2006
Filed:
Dec. 07, 2001
Applicants:
Frank Blecha, Manhattan, KS (US);
Jishu Shi, Los Angeles, CA (US);
Inventors:
Frank Blecha, Manhattan, KS (US);
Jishu Shi, Los Angeles, CA (US);
Assignee:
Kansas State University Research Foundation, Manhattan, KS (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods of inhibiting leukocyte Oproduction and attracting leuckocytes using specific peptides are disclosed. These peptides include the proline-arginine (PR)-rich antimicrobial peptide known as PR-39 and truncated analogs thereof. These peptides can be used as medicaments that fight infection by attracting leukocytes to a wound site, yet restrict tissue damage at the wound site caused by excessive oxygen radicals produced by these leukocytes.