The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2006

Filed:

Dec. 17, 2002
Applicants:

Sunil Paliwal, Scotch Plains, NJ (US);

Gregory A. Reichard, Ann Arbor, MI (US);

Cheng Wang, Summit, NJ (US);

Dong Xiao, Warren, NJ (US);

Hon-chung Tsui, East Brunswick, NJ (US);

Neng-yang Shih, North Caldwell, NJ (US);

Juan D. Arredondo, Montclair, NJ (US);

Michelle Laci Wrobleski, Whitehouse Station, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Inventors:

Sunil Paliwal, Scotch Plains, NJ (US);

Gregory A. Reichard, Ann Arbor, MI (US);

Cheng Wang, Summit, NJ (US);

Dong Xiao, Warren, NJ (US);

Hon-Chung Tsui, East Brunswick, NJ (US);

Neng-Yang Shih, North Caldwell, NJ (US);

Juan D. Arredondo, Montclair, NJ (US);

Michelle Laci Wrobleski, Whitehouse Station, NJ (US);

Anandan Palani, Bridgewater, NJ (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 221/20 (2006.01);
U.S. Cl.
CPC ...
Abstract

A NKantagonist having the formula (I), wherein Arand Arare optionally substituted phenyl or heteroaryl, Xis an ether, thio or imino linkage, Rand Rare not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.


Find Patent Forward Citations

Loading…