The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2006

Filed:

Jun. 02, 2000
Applicants:

Paul Rafferty, Nottingham, GB;

David Calderwood, Nottingham, GB;

Lee Arnold, Westborough, MA (US);

Beatriz Gonzalez Pascual, Madrid, ES;

Jose L. Ortego Martinez, Madrid, ES;

Maria J. Perez DE Vega, Madrid, ES;

Isabel Fernandez, Madrid, ES;

Inventors:

Paul Rafferty, Nottingham, GB;

David Calderwood, Nottingham, GB;

Lee Arnold, Westborough, MA (US);

Beatriz Gonzalez Pascual, Madrid, ES;

Jose L. Ortego Martinez, Madrid, ES;

Maria J. Perez de Vega, Madrid, ES;

Isabel Fernandez, Madrid, ES;

Assignee:

Abbott GmbH & Co. KG, Wiesbaden, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); A61K 31/5415 (2006.01); A61K 31/542 (2006.01);
U.S. Cl.
CPC ...
Abstract

Chemical compounds having structural formula I and physiologically acceptable salts thereof, are inhibitors of serine/threonine and tyrosine kinase activity. Several of the tyrosine kinases, whose activity is inhibited by these chemical compounds, are involved in angiogenic processes. Thus, these chemical compounds can ameliorate disease states where angiogenesis or endothelial cell hyperproliferation is a factor. These compounds can be used to treat cancer and hyperproliferative disorders.


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