The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 2006

Filed:

Feb. 28, 2002
Applicants:

Frank P. Luyten, Kraainem, BE;

Malcolm Moos, Jr., Bethesda, MD (US);

Bang Hoang, New York, NY (US);

Shouwen Wang, Levittown, PA (US);

Inventors:

Frank P. Luyten, Kraainem, BE;

Malcolm Moos, Jr., Bethesda, MD (US);

Bang Hoang, New York, NY (US);

Shouwen Wang, Levittown, PA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); C07K 14/475 (2006.01); C07K 14/51 (2006.01);
U.S. Cl.
CPC ...
Abstract

An isolated cDNA encoding a growth-inducing protein, Frzb, capable of stimulating bone, cartilage, muscle and nerve tissue formation. Frzb binds to and modulates the activity of Wnt growth factors which play a role in various developmental and neoplastic processes. The cDNA and protein sequences of human, bovine andFrzb are provided. Production and purification of recombinant Frzb are also described.


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