The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 23, 2006
Filed:
Apr. 24, 2002
Fons Bosman, Opwijk, BE;
Erik Depla, Destelbergen, BE;
Geert Deschamps, Aalter, BE;
Erwin Sablon, Merchtem, BE;
Isabelle Samson, Heule, BE;
Annie Van Broekhoven, Berchem, BE;
Joost Haelewyn, Ghent, BE;
Fons Bosman, Opwijk, BE;
Erik Depla, Destelbergen, BE;
Geert Deschamps, Aalter, BE;
Erwin Sablon, Merchtem, BE;
Isabelle Samson, Heule, BE;
Annie Van Broekhoven, Berchem, BE;
Joost Haelewyn, Ghent, BE;
Innogenetics N.V., Ghent, BE;
Abstract
The present invention relates to the general field of recombinant protein expression, purification of recombinant proteins, diagnosis of HCV infection, prophylactic treatment against HCV infection and to the prognosing/monitoring of the clinical efficiency of treatment of an individual with chronic hepatitis, or the prognosing/monitoring of the natural disease. In particular, the present invention relates to the use of yeast, i.e.orglycosylation minus strains, for the efficient expression of HCV envelope proteins that are core-glycosylated, purification methods for these proteins, and the use in various applications, such as the use in diagnosis, prophylaxis or therapy of HCV envelope proteins purified according to the present invention.