The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 2006

Filed:

Aug. 10, 1999
Applicants:

Roy A. Gravel, Calgary, CA;

Rima Rozen, Montreal West, CA;

Daniel Leclerc, Montreal, CA;

Aaron Wilson, Montreal, CA;

David Rosenblatt, Montreal, CA;

Inventors:

Roy A. Gravel, Calgary, CA;

Rima Rozen, Montreal West, CA;

Daniel Leclerc, Montreal, CA;

Aaron Wilson, Montreal, CA;

David Rosenblatt, Montreal, CA;

Assignee:

McGill University, Montreal, CA;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/53 (2006.01); C12N 9/02 (2006.01); C12N 15/00 (2006.01); C12N 5/00 (2006.01); C12N 1/20 (2006.01); C12Q 1/26 (2006.01); C12P 21/06 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention features a novel gene encoding methionine synthase reductase. The invention also features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects, cardiovascular disease, or cancer. The invention also features therapeutic methods for treating and/or reducing the risk of cardiovascular disease, cancer, or neural tube defects. Also provided are the sequences of the human methionine synthase reductase gene and protein and compounds and kits for performing the methods of the invention.


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