The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 16, 2006
Filed:
Oct. 25, 2001
Gerd Gellissen, Wülfrath, DE;
Gerhard Braus, Goettingen, DE;
Ralph Pries, Goettingen, DE;
Sven Krappmann, Goettingen, DE;
Alexander W. Strasser, Dusseldorf, DE;
Gerd Gellissen, Wülfrath, DE;
Gerhard Braus, Goettingen, DE;
Ralph Pries, Goettingen, DE;
Sven Krappmann, Goettingen, DE;
Alexander W. Strasser, Dusseldorf, DE;
Abstract
The invention relates to a nucleic acid molecule, comprising a nucleic acid which codes for a polypeptide with chorismate mutase activity and derivatives thereof, whereby the derivatives have at least 10% of the chorismate mutase activity of the chorismate mutase, according to the identification number of the SEQ ID NO:2. The invention further relates to vectors containing nucleic acid molecules, to host cells comprising nucleic acid molecules and their use in methods for producing polypetides with chorismate mutase activity. The invention also relates to the polypeptides with chorismate mutase activity and antibodies which specifically recognize the same. In addition, the invention relates to methods for producing auxotrophic yeast strains using the nucleic acid molecules and to the preparation of the yeast strains. The invention also relates to the use of yeast strains together with the inventive vectors in methods for the recombinant expression of heterologous genes which allow the transformants to be easily selected by functional complementation.