The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2006
Filed:
Nov. 18, 2003
Applicants:
Perry Rosen, Seattle, WA (US);
Kwang Nho, Orinda, CA (US);
Inventors:
Perry Rosen, Seattle, WA (US);
Kwang Nho, Orinda, CA (US);
Assignee:
Sun Bio, Inc., Orinda, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07C 47/02 (2006.01); C07C 233/00 (2006.01); C08G 63/48 (2006.01); C08L 61/02 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides novel monofunctional polyethylene glycol aldehydes for the pegylation of therapeutically active proteins. The pegylated protein conjugates that are produced, retain a substantial portion of their therapeutic activity and are less immunogenic than the protein from which the conjugate is derived. New syntheses for preparing such aldehydes are described.