The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 09, 2006

Filed:

Mar. 14, 2003
Applicants:

Hank F. Kung, Wynnewood, PA (US);

Chyng-yann Shiue, Villanova, PA (US);

Shunichi Oya, Princeton Junction, NJ (US);

Seok Rye Choi, Drexel Hill, PA (US);

Grace G. Shiue, Villanova, PA (US);

Ping Fang, Drexel Hill, PA (US);

Inventors:

Hank F. Kung, Wynnewood, PA (US);

Chyng-Yann Shiue, Villanova, PA (US);

Shunichi Oya, Princeton Junction, NJ (US);

Seok Rye Choi, Drexel Hill, PA (US);

Grace G. Shiue, Villanova, PA (US);

Ping Fang, Drexel Hill, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 321/28 (2006.01); C07C 321/30 (2006.01); A61K 31/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to novel fluorinated phenyl thiphenyl (also named diarylsulfide) derivatives and their use in Positron Emission Tomagraphy (PET) imaging of Serotonin Transporters (SERTS). The present invention also provides diagnostic compositions comprising the novel compounds of the present invention, and a pharmaceutically acceptable carrier or diluent. The invention further provides a method of imaging SERTS, comprising introducing into a patient a detectable quantity of a labeled compound of the present invetion, or a pharmaceutically acceptable salt, ester, amide or prodrug thereof.


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