The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2006
Filed:
Mar. 29, 2002
Toshiyuki Watai, Takaoka, JP;
Mitsuru Takase, Niigata, JP;
Takahiro Sagae, Odawara, JP;
Shigeo Mori, Niigata, JP;
Noriaki Kawahara, Niigata, JP;
Toshiyuki Watai, Takaoka, JP;
Mitsuru Takase, Niigata, JP;
Takahiro Sagae, Odawara, JP;
Shigeo Mori, Niigata, JP;
Noriaki Kawahara, Niigata, JP;
Nippon Soda Co., Ltd., Tokyo, JP;
Daiichi Asubio Pharma Co., Ltd., Tokyo, JP;
Abstract
There is provided a method by which various compounds (1) having a carboxyl group in the molecule have the carboxyl group converted to a (dioxolenon-4-yl)methyl ester at low cost, in a simple way and at high yield. The process for producing compounds of formula (3) according to the reaction scheme shown below comprises reacting carboxylic acids of formula (1) with 4-chloromethyldioxolenone compounds of formula (2) in a solvent in the presence of both a phase transfer catalyst and a metal iodide: [where Q represents an organic group, M represents a hydrogen atom, an alkali metal, an alkaline earth metal or a transition metal, Rand Rrepresent a hydrogen atom, an optionally substituted (Calkyl group or phenyl group)].