The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2006
Filed:
Jan. 25, 1999
Thomas Quertermous, Nashville, TN (US);
Brigid Hogan, Brentwood, TN (US);
H. Ralph Snodgrass, Powell, OH (US);
Thomas Joel Zupancic, Worthington, OH (US);
Thomas Quertermous, Nashville, TN (US);
Brigid Hogan, Brentwood, TN (US);
H. Ralph Snodgrass, Powell, OH (US);
Thomas Joel Zupancic, Worthington, OH (US);
Abstract
The present invention relates to a member of a novel gene family referred to as developmentally-regulated endothelial cell locus-1 (del-1). In particularly, the invention related to del-1 nucleotide sequences, Del-1 amino acid sequences, methods of expressing a functional gene product, and methods of using the gene and gene product. Since del-1 is expressed in endothelial cells and certain cancer cells, it may be useful as an endothelial cell and tumor marker. In addition, anti-Del-1 antibodies for immunological assessment of Del-1 protein expression as well as for inhibiting or stimulating Del-1 function are provided.