The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2006
Filed:
May. 24, 2002
Ronald M. Evans, La Jolla, CA (US);
Barry M. Forman, Newport Beach, CA (US);
Cary A. Weinberger, Carrboro, NC (US);
Ronald M. Evans, La Jolla, CA (US);
Barry M. Forman, Newport Beach, CA (US);
Cary A. Weinberger, Carrboro, NC (US);
The Salk Institute for Biological Studies, La Jolla, CA (US);
Ligand Pharmaceuticals, Inc., San Diego, CA (US);
The Government of the United States of America, Washington, DC (US);
Abstract
Farnesyl pyrophosphate, the metabolically active form of farnesol, is a key precursor in the synthesis of cholesterol, carotenoids, steroid hormones, bile acids and other molecules involved in cellular growth and metabolism. A nuclear receptor has been identified that is transcriptionally activated by farnesol and related molecules. This novel signaling pathway can be modulated by the use of key metabolic intermediates (or analogs and/or derivatives thereof) as transcriptional regulatory signals.