The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2006
Filed:
Jun. 05, 2001
Herman F. Staats, Durham, NC (US);
Barton F. Haynes, Durham, NC (US);
Dhavalkumar D. Patel, Durham, NC (US);
Gregory D. Sempowski, Durham, NC (US);
Herman F. Staats, Durham, NC (US);
Barton F. Haynes, Durham, NC (US);
Dhavalkumar D. Patel, Durham, NC (US);
Gregory D. Sempowski, Durham, NC (US);
Duke University, Durham, NC (US);
Abstract
A method of eliciting an immune response against an antigen in a vertebrate subject, the method comprising the steps of providing an antigen-adjuvant composition comprising the antigen and a substantially non-toxic adjuvant molecule having biological activity in mucosal tissues, and administering said antigen-adjuvant composition to the vertebrate subject in a manner such that initial contact occurs in mucosal tissue of the vertebrate subject, whereby an immune response is elicited. Cytokines are preferred adjuvants. Preferred cytokines are interleukin-1α(IL-1α) and interleukin-1β (IL-1β).