The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 2006
Filed:
Jun. 27, 2002
Stephen Randall Holmes-farley, Arlington, MA (US);
W. Harry Mandeville, Iii, Lynnfield, MA (US);
Pradeep K. Dhal, Westford, MA (US);
Chad Cori Huval, Somerville, MA (US);
Xinhua LI, Newton, MA (US);
Steven Craig Polomoscanik, Bedford, MA (US);
Stephen Randall Holmes-Farley, Arlington, MA (US);
W. Harry Mandeville, III, Lynnfield, MA (US);
Pradeep K. Dhal, Westford, MA (US);
Chad Cori Huval, Somerville, MA (US);
Xinhua Li, Newton, MA (US);
Steven Craig Polomoscanik, Bedford, MA (US);
Genzyme Corporation, Cambridge, MA (US);
Abstract
Disclosed are polymers comprising one or more phenyl boronate ester, boronamide or boronate thioester groups. The phenyl boronate ester, boronamide and boronate thioester groups are represented by one of the following structural formulas: Ar in Structural Formulas (I) and (II) is substituted or unsubstituted; and each Z is —O—, —NH— or —S— and is independently selected. Pharmaceutically acceptable salts of the polymer are also included. The aryl boronate ester, boronamide or boronate thioester can be cleaved to release the corresponding aryl boronic acid. Also disclosed are pharmaceutical compositions comprising the polymers of the present invention and a pharmaceutically acceptable carrier or diluent; and methods of treating a subject for obesity with the polymers of the present invention.