The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
May. 19, 2003
Applicants:
Rami Lidor-hadas, Kfar Saba, IL;
Zvi Harel, Kfar Saba, IL;
Revital Lifshitz-liron, Herzlia, IL;
Eti Kovalevski, Netanya, IL;
Inventors:
Rami Lidor-Hadas, Kfar Saba, IL;
Zvi Harel, Kfar Saba, IL;
Revital Lifshitz-Liron, Herzlia, IL;
Eti Kovalevski, Netanya, IL;
Assignee:
Teva Pharmaceutical Industries, Ltd., Petah Tiqva, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
Provided is a novel method of making bisphosphonic acids, e.g. risedronic acid, including the step of combining a carboxylic acid, phoshorous acid, and a halophosphorous compound in the presence of a diluent that is an aromatic hydrocarbon or a silicone fluid. When the diluent is an aromatic hydrocarbon, a inert support or ortho-phosphoric acid codiluent is advantageously included.