The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
Dec. 04, 2003
Masahide Tanaka, Osaka, JP;
Kozo Matsui, Osaka, JP;
Tadashi Katsura, Osaka, JP;
Mitsuhiro Iwasaki, Osaka, JP;
Hiroshi Maeda, Osaka, JP;
Nobushige Itaya, Osaka, JP;
Masahide Tanaka, Osaka, JP;
Kozo Matsui, Osaka, JP;
Tadashi Katsura, Osaka, JP;
Mitsuhiro Iwasaki, Osaka, JP;
Hiroshi Maeda, Osaka, JP;
Nobushige Itaya, Osaka, JP;
Sumitomo Chemical Company, Limited, Tokyo, JP;
Abstract
The present invention relates to a production method of (R)-3-hydroxy-3-(2-phenylethyl)hexanoic acid which comprises optical resolution of racemic 3-hydroxy-3-(2-phenylethyl)hexanoic acid with an optically active amine of the formula (VIII)wherein Ris 3,4-dimethoxyphenyl or 2-chlorophenyl. According to the present invention, (R)-3-hydroxy-3-(2-phenylethyl)hexanoic acid useful as a starting material of a pharmaceutical agent can be efficiently produced with a high optical purity and a relatively high total yield.