The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
May. 15, 2003
Mukund S. Chorghade, Natick, MA (US);
Mukund K. Gurjar, Pune Maharashtra, IN;
Bhanu M. Chanda, Pune Maharashtra, IN;
Mukund S. Chorghade, Natick, MA (US);
Mukund K. Gurjar, Pune Maharashtra, IN;
Bhanu M. Chanda, Pune Maharashtra, IN;
Genzyme Corporation, Cambridge, MA (US);
Abstract
A method of preparing a 2-alkyl amino acid involves the aziridination of an alkylacrylate and the opening of the aziridine ring by addition of a side chain. This method can result in the preparation of enantiomeric excess of a 2-alkyl amino acid. The invention also discloses a method of preparing a class of iron chelating agents related to desferrithiocin, all of which contain a thiazoline ring. In this method, an aryl nitrile or imidate is condensed with cysteine, a 2-alkyl cysteine, or a cysteine ester.