The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 02, 2006

Filed:

Feb. 13, 2001
Applicants:

Hironori Komatsu, Chiba, JP;

Hirokazu Awano, Chiba, JP;

Nobuyuki Fukazawa, Chiba, JP;

Kiyoshi Ito, Chiba, JP;

Ichirou Ikeda, Chiba, JP;

Tadashi Araki, Chiba, JP;

Takeshi Nakamura, Chiba, JP;

Tamotsu Asano, Chiba, JP;

Junya Fujiwara, Chiba, JP;

Tomoyuki Ando, Chiba, JP;

Katsutoshi Tsuchiya, Chiba, JP;

Kyoko Maruyama, Chiba, JP;

Hideki Umetani, Chiba, JP;

Takahiro Yamauchi, Chiba, JP;

Hitoki Miyake, Chiba, JP;

Inventors:

Hironori Komatsu, Chiba, JP;

Hirokazu Awano, Chiba, JP;

Nobuyuki Fukazawa, Chiba, JP;

Kiyoshi Ito, Chiba, JP;

Ichirou Ikeda, Chiba, JP;

Tadashi Araki, Chiba, JP;

Takeshi Nakamura, Chiba, JP;

Tamotsu Asano, Chiba, JP;

Junya Fujiwara, Chiba, JP;

Tomoyuki Ando, Chiba, JP;

Katsutoshi Tsuchiya, Chiba, JP;

Kyoko Maruyama, Chiba, JP;

Hideki Umetani, Chiba, JP;

Takahiro Yamauchi, Chiba, JP;

Hitoki Miyake, Chiba, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/665 (2006.01); A61K 31/7024 (2006.01); C07F 9/6544 (2006.01);
U.S. Cl.
CPC ...
Abstract

A desired isomer is selectively prepared by phosphorolyzing and isomerizing an anomer mixture of a 1-phosphorylated saccharide derivative while crystallizing one of the isomers to displace the equilibrium. Furthermore, using the action of a nucleoside phosphorylase, a nucleoside is prepared from the 1-phosphorylated saccharide derivative obtained and a base with improved stereoselectivity and a higher yield. This process is an anomer-selective process for preparing a 1-phosphorylated saccharide derivative and a nucleoside.


Find Patent Forward Citations

Loading…