The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
Dec. 04, 2002
Ricardo Agustin Lopez, Autonama de Buenos Aires, AR;
Ricardo Agustin Lopez, Autonama de Buenos Aires, AR;
Immunotech S.A., Ciudad Autonoma de Buenos Aires, AR;
Abstract
Oligonucleotides containing the non-palindromic sequence motif:XXXXXXXX,wherein Xis C,T,G or A (preferably T or C); wherein Xis C,T,G or A; wherein Xis C,T,G or A (preferably G); at least three, and preferably all, of X, X, X, Xand Xare T; and with the proviso that, in the motif, a C does not precede a G (in other terms, the nucleic acid motif does not consist of a CpG oligonucleotide), that modulate the immune response of animals of the order Primate, including humans, are disclosed. This immune modulation is characterized by stimulation of proliferation, differentiation, cytokine production and antibody production on B-cells and cell differentiation on plasmacytoid dendritic cells.