The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
Oct. 12, 2001
Applicants:
Jorge Dimartino, San Carlos, CA (US);
John Tippett Nelson, Danville, CA (US);
Inventors:
Jorge DiMartino, San Carlos, CA (US);
John Tippett Nelson, Danville, CA (US);
Assignee:
SuperGen, Inc., Dublin, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/40 (2006.01); A61K 31/70 (2006.01);
U.S. Cl.
CPC ...
Abstract
Compositions and methods are provided for prevention and clinical treatment of various forms of graft-versus-host disease (GVHD) by using inhibitors of adenosine deaminase (ADA). In particular, various formulations and dosing regimens of ADA inhibitors such as pentostatin are provided for the treatment of humans in vivo as well as for ex vivo conditioning of organ transplants in order to specifically suppress T-lymphocyte mediated immune responses while minimizing systemic toxicity of the drug.