The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
Jul. 19, 2002
Yoshimasa Saito, Kawanishi, JP;
Yoshiko Ueda, Osaka, JP;
Kouichi Tamura, Kobe, JP;
Yoko Takata, Osaka, JP;
Hisashi Yamada, Sanda, JP;
Tatsuo Yamashita, Kobe, JP;
Masakazu Kobayashi, Takarazuka, JP;
Yoshimasa Saito, Kawanishi, JP;
Yoshiko Ueda, Osaka, JP;
Kouichi Tamura, Kobe, JP;
Yoko Takata, Osaka, JP;
Hisashi Yamada, Sanda, JP;
Tatsuo Yamashita, Kobe, JP;
Masakazu Kobayashi, Takarazuka, JP;
Astellas Pharma Inc., Tokyo, JP;
Abstract
This invention relates to a hematopoietic stem cell proliferating agent comprising IGF-I, a hematopoietic stem cell proliferating agent comprising IGF-I and at least one protein selected from among SCF, M-CSF, and G-CSF, and a method of growing hematopoietic stem cells which comprises culturing hematopoietic stem cells in a medium containing IGF-I and at least one protein selected from the group consisting of SCF and M-CSF. The hematopoietic stem cell proliferating agent of the invention causes hematopoietic stem cells to proliferate in the undifferentiated state whether in vivo or in vitro and can, therefore, be used for amelioration of the cytopenia induced by radiotherapy or chemotherapy using anticancer drugs, prevention of infectious diseases associated with lymphopenia, or in vitro culture for multiplication of hematopoietic stem cells and extrasomatic culture of recombinant stem cells in gene therapy.