The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
May. 25, 2001
Simon Barry, Macclesfield, GB;
Carmel Horgan, Stevenage, GB;
Steven Ludbrook, Stevenage, GB;
David Miller, Stevenage, GB;
Simon Barry, Macclesfield, GB;
Carmel Horgan, Stevenage, GB;
Steven Ludbrook, Stevenage, GB;
David Miller, Stevenage, GB;
SmithKline Beecham Corporation, Philadelphia, PA (US);
Abstract
A method for the identification of a modulator of the interaction between latency asssociated peptide (LAP) of transforming growth factor β1 (TGF-β1) and the integrin ab, which method comprises: (a) providing, as a first component, LAP-β1 or a functional variant thereof (b) providing, as a second component, integrin abor a functional variant thereof (c) contacting the two components with a test product under conditions that, in the absence of the test product, would permit the two components to interact; and (d) determining whether the test product is capable of modulating the interaction between the first and second components, thereby to determine whether the test product is a modulator of the interaction between LAP-β1 and integrin ab.