The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
Nov. 06, 2002
Applicants:
Jack Summers, Baltimore, MD (US);
Michael Sturgess, Quakertown, PA (US);
John Shimko, Baltimore, MD (US);
Inventors:
Jack Summers, Baltimore, MD (US);
Michael Sturgess, Quakertown, PA (US);
John Shimko, Baltimore, MD (US);
Assignee:
Message Pharmaceuticals, Malvern, PA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention features methods for detecting and quantifying the binding or inhibition of binding of species to biopolymers, e.g., nucleic acids. The invention is based on the use of probes that have magnetic relaxation properties that are affected by the presence of paramagnetic metal ions, e.g., Mn. Any class of biopolymer that binds metal ions at its active site or uses metal ion cofactors can be studied using these methods.