The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 02, 2006
Filed:
Dec. 15, 2000
Hideyo Uchiwa, Odawara, JP;
Sachiyo Hirotsu, Odawara, JP;
Akinori Haratake, Odawara, JP;
Takeshi Ikemoto, Minamiasigara, JP;
Junichi Matsui, Odawara, JP;
Shunsuke Yamazaki, Odawara, JP;
Masaki Yoshida, Odawara, JP;
Motoi Hayase, Odawara, JP;
Hideyo Uchiwa, Odawara, JP;
Sachiyo Hirotsu, Odawara, JP;
Akinori Haratake, Odawara, JP;
Takeshi Ikemoto, Minamiasigara, JP;
Junichi Matsui, Odawara, JP;
Shunsuke Yamazaki, Odawara, JP;
Masaki Yoshida, Odawara, JP;
Motoi Hayase, Odawara, JP;
Kanebo Cosmetics, Inc., Tokyo, JP;
Abstract
Skin external agent compositions and drugs characterized by containing fumaric acid diester derivatives represented by following general formula (1), wherein Rrepresents Calkylene; Rand Rrepresent each liner or branched Calkyl; and n is an integer of 2 to 5; which provide epidermal barrier function potentiating agents and skin external agent compositions having a high safety, quickly relieving epidermal permeation barrier function failures and having an effect of maintaining the skin in a cosmetologically healthy state; agents to be used together with HB-EFG expression inducing agents accelerating epidermal turnover, amphiregulin expression inhibitors regulating excessive epidermal proliferation, and retinoic acid or its derivative preventing skin chapping caused by retinoic acid or its derivative; and skin aging relieving agents capable of ameliorating depression in the skin metabolism and thinning in association with aging.