The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2006
Filed:
Oct. 21, 2002
Charles A. Blum, Westbrook, CT (US);
Harry L. Brielmann, Guilford, CT (US);
Stephane DE Lombaert, Madison, CT (US);
Xiaozhang Zheng, Branford, CT (US);
Charles A. Blum, Westbrook, CT (US);
Harry L. Brielmann, Guilford, CT (US);
Stephane De Lombaert, Madison, CT (US);
Xiaozhang Zheng, Branford, CT (US);
Neurogen Corporation, Branford, CT (US);
Abstract
Substituted 2-cyclohexyl-4-phenyl-1H-imidazole derivatives capable of modulating NPY5 receptor activity, are provided. Such compounds may be used to modulate NPY binding to NPY5 receptors in vivo or in vitro, and are particularly useful in the treatment of a variety of disorders (e.g., eating disorders such as obesity or bulimia, psychiatric disorders, diabetes and cardiovascular disorders such as hypertension) in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for treating such disorders are provided, as are methods for using such compounds for detecting NPY5 receptors.