The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2006
Filed:
May. 03, 2001
Michael Joseph Kukla, Maple Glen, PA (US);
Donald William Ludovici, Quakertown, PA (US);
Robert William Kavash, Glenside, PA (US);
Bart Lieven Daniel DE Corte, Southampton, PA (US);
Jan Heeres, Vosselaar, BE;
Paul Adriaan Jan Janssen, Vosselaar, BE;
Lucien Maria Henricus Koymans, Retie, BE;
Marc René DE Jonge, Tilburg, NL;
Koen Jeanne Alfons Van Aken, Kortrijk, BE;
Alain Krief, Namur, BE;
Michael Joseph Kukla, Maple Glen, PA (US);
Donald William Ludovici, Quakertown, PA (US);
Robert William Kavash, Glenside, PA (US);
Bart Lieven Daniel De Corte, Southampton, PA (US);
Jan Heeres, Vosselaar, BE;
Paul Adriaan Jan Janssen, Vosselaar, BE;
Lucien Maria Henricus Koymans, Retie, BE;
Marc René de Jonge, Tilburg, NL;
Koen Jeanne Alfons Van Aken, Kortrijk, BE;
Alain Krief, Namur, BE;
Janssen Pharmaceutica N.V., Beerse, BE;
Abstract
The present invention concerns compounds of formula (A)(A)N—R(I),the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and stereochemically isomeric forms thereof, wherein Ris substituted Calkyl; —S(═O)—R; —S(═O)—R; Calkylcarbonyl; optionally substituted CalkyloxycarbonylCalkylcarbonyl; with Rbeing Calkyl, arylor Het; (A)(A)N— is the covalently bonded form of the corresponding intermediate of formula (A)(A)N—H, which is a HIV replication inhibiting pyrimidine of formula