The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2006
Filed:
Mar. 15, 2002
Naoya Kobayashi, Okayama-shi, Okayama 703-8261, JP;
Philippe Leboulch, Charlestown, MA (US);
Noriaki Tanaka, Okayama 719-0252, JP;
Toshiyoshi Fujiwara, Okayama-shi, Okayama 703-8281, JP;
Toshinori Totsugawa, Fukuyama-shi, Hiroshima 720-0836, JP;
Naoya Kobayashi, Okayama-shi, Okayama 703-8261, JP;
Philippe Leboulch, Charlestown, MA (US);
Noriaki Tanaka, Okayama 719-0252, JP;
Toshiyoshi Fujiwara, Okayama-shi, Okayama 703-8281, JP;
Toshinori Totsugawa, Fukuyama-shi, Hiroshima 720-0836, JP;
Other;
Abstract
The present invention provides a method comprising a step of transferring a cell proliferation factor gene into a mammalian liver cell to obtain an immortalized liver cell, a step of proliferating the immortalized liver cell, and a step of removing the cell proliferation factor gene from the immortalized liver cell; a large number of liver cells obtained thereby; and a treating agent and a artificial liver comprising obtained liver cell.