The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 25, 2006

Filed:

Jun. 22, 1999
Applicants:

Ramasubbu Jevanthi, Columbia, MD (US);

John E. Van Hamont, Fort Meade, MD (US);

Phil Friden, Bedford, MA (US);

Robert H. Reid, Fairfield, PA (US);

F. Donald Roberts, Dover, MA (US);

Charles E. Mcqueen, Olney, MD (US);

Jean A. Setterstrom, Silver Spring, MD (US);

Inventors:

Ramasubbu Jevanthi, Columbia, MD (US);

John E. Van Hamont, Fort Meade, MD (US);

Phil Friden, Bedford, MA (US);

Robert H. Reid, Fairfield, PA (US);

F. Donald Roberts, Dover, MA (US);

Charles E. McQueen, Olney, MD (US);

Jean A. Setterstrom, Silver Spring, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
Abstract

Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1–100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer as a blend of uncapped (free carboxyl end group) and end-capped forms ranging in ratios from 100/0 to 1/99.


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