The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 25, 2006
Filed:
Nov. 08, 2002
Applicants:
Yun H. Choe, Green Brook, NJ (US);
Richard B. Greenwald, Somerset, NJ (US);
Inventors:
Yun H. Choe, Green Brook, NJ (US);
Richard B. Greenwald, Somerset, NJ (US);
Assignee:
Enzon Pharmaceuticals, Inc., Bridgewater, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/74 (2006.01); A61K 31/75 (2006.01);
U.S. Cl.
CPC ...
Abstract
Thiol-linked polymeric prodrugs and methods of making and using the same are disclosed. The use of a sulfhydryl bond as the basic link for linking the polymer to the drug allows a prodrug to be formed which takes advantage of plasma enzymes in vivo. A preferred conjugate isMethods of preparing and treatment are also disclosed.