The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 2006
Filed:
Oct. 28, 2004
Applicants:
YE Wu, Helotes, TX (US);
Kesavaram Narkunan, San Antonio, TX (US);
Jianyan Wang, Helotes, TX (US);
Harry Kochat, San Antonio, TX (US);
Inventors:
Ye Wu, Helotes, TX (US);
Kesavaram Narkunan, San Antonio, TX (US);
Jianyan Wang, Helotes, TX (US);
Harry Kochat, San Antonio, TX (US);
Assignee:
BioNumerik Pharmaceuticals, Inc., San Antonio, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/22 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for synthesizing highly lipophilic derivatives of camptothecin. The process includes reacting dissolved, underivatized camptothecin with a silylated heterocyclic compound in a modified Minisci-type alkylation reaction to produce 7-substituted derivatives of camptothecin.